In a future where technology has advanced to the point where humans can undergo "optimization" to rid themselves of emotions and increase their mental functions, one man decides to cling to his humanity in an effort to atone for his sins and appreciate the beauty of being human.

Is it better to have a human civilization devoid of art and culture than to have none at all? Three Earth ambassadors must whether to annihilate a space colony that has traded away human consciousness for a hive mind that feels nothing but the need for survival. In the distant future, three humans in possession of nuclear warheads must decide whether to allow a remarkable human variant species without consciousness to dominate the galaxy or destroy them forever.

A few men gather in a small house to discuss what makes humanity unique as compared to the rest of nature.

Professor gives a talk about the human appetite for death

In the year 2033, a reviewer for a novel written by an algorithmic recreation of Isaac Asimov’s brain believes the work acts as a reverse Turing Test, prodding the self-consciousness of its human readers through its unorthodox construction. According to a think piece written by a fictitious reviewer in the year 2033, a novel written by a simulation of Isaac Asimov's brain is capable of interrogating humans about their own self-consciousness.

In this metafiction, the many lives of an unnamed man are scrutinized as he passes through millennia.

In intense discussion a group leader ponders aloud, asking why hermits hide and what defines outcasts, among other cerebral queries. A group of friends discusses the oddities they have seen and perceived in their lives leather-clad hermits and criminal astronauts among them. They debate the purpose of hermitage, the classification of outcasts, and the purpose of their own reflections.

A research psychologist visits a peculiar asylum patient who recounts his life story. The patient warns the researcher about how obsession with the pursuit of knowledge can make one lose sight of their humanity until it is unsalvageable.

A middle-aged man faces a difficult decision; he can choose to use genetic alteration to have a say over the life of his unborn child, or leave the future up to chance. As he struggles to choose a path, he reconsiders his own past and the struggles he has faced.

In discussing the altercations witnessed over the course of the day, Stephen Elwin and his family grapple with question of whether the downtrodden and those burdened by prejudice are nonetheless responsible for their own breeding and behavior. Elwin’s earnest and idealistic daughter Margaret valiantly defends their maid, who happens to be Black and also named Margaret, until she witnesses 'the other Margaret' breaking a piece of artwork.