A drug counselor grows anxious about leaving her career in New York City and moving upstate, where she will dedicate herself to her partner and daughter.

A woman addicted to narcotics works as a waitress and fixes up her apartment in hopes of getting back her son from foster care after throwing him against a wall.

A young teen in Southern California, after several months of living on the streets, tries to rebuild her life. She suddenly disappears after six months of sobriety, leaving her family to yet again wonder if she has relapsed and returned to live on the streets again.

A mother reflects on her past struggles with addiction.

When a sober woman in her thirties meets a strange man involved in high-profile drug deals, she is horrified to learn that he has followed her for weeks. Eventually, the woman goes against her better judgement and begins to date him after he promises her a life of luxury and comfort.

When the father of her baby overdoses, a young mother with a crippling drug addiction hits rock bottom much faster than she thought possible. All the while, she must take care of her son and figure out how to survive.

A grieving sheriff takes it upon himself to battle the opium epidemic in his area after losing his nephew and wife to a drug dealer known only as the "hellbender."

A man must hunt down his painkiller-addicted ex-boyfriend and attempt to rescue the ex from his drug dealer.

A counselor breaks his sobriety streak after several meetings with a frustrating client. After arguing with his wife while drunk, the counselor begins to feel murderous and must fight his violent urges to earn back her trust.

In the first personal plural, a psychiatric ward patient describes their day-to-day routines and thoughts while their life slowly becomes easier.