Debilitating, apparently incurable migraines confine a graduate student to the hospital. When one of her roommates, a strange woman with multiple personality disorder, takes an interest in her, the student's world begins to collapse.

A woman's chronic illness stirs up long-suppressed conflict within her family. As she helplessly listens to her husband and brother-in-law argue about the best treatments, she wishes she could be there to defend her troubled husband.

After accidentally killing a friend's baby, a 35 year old woman tries to find her footing again at her husband's academic conference in Europe—but finds herself struggling with herself and her marriage.

An academic who is dying from breast cancer and high on morphine reflects on her sense of failure in her lifelong pursuit of artistic brilliance. She decides her failing body has become her great work of art.

Three months after the death of his wife, a man tries to convince himself that he has not truly suffered a loss, all the while missing his wife more than ever.

Having been hospitalized for a long time, a young girl finds herself surrounded by people who cannot understand the strangeness of her illness. After her friend visits her, she must accept that her relationships may never be the same, and that her expectations that tether her to a life outside of the hospital may be very different from the disappointing reality.

After a terrible accident, a boy and his family spend the next years in a depression that verges masochism.

A divorced 16 year old girl reflects on how the sexual trauma she experienced as a child perpetuates in her relationships with men throughout her life, forcing herself to grow up too early and leaving her starved for affection and love.

A brother and his sister disagree fundamentally on how to care for their dying mother. Death approaches sooner than anticipated, leaving the brother feeling lonelier than ever.

Faced with inexplicable suffering in a locked ward of a mental hospital, a young woman must choose whether to give up or live life on her own terms.