A woman addicted to narcotics works as a waitress and fixes up her apartment in hopes of getting back her son from foster care after throwing him against a wall.

When the father of her baby overdoses, a young mother with a crippling drug addiction hits rock bottom much faster than she thought possible. All the while, she must take care of her son and figure out how to survive.

As he flushes three decades of narcotics out of his system, an Arkansas man recalls a traumatic hunting trip into the woods with his father and his friends. In this memory, he finds the roots of both his addiction and his identity.

When a sober woman in her thirties meets a strange man involved in high-profile drug deals, she is horrified to learn that he has followed her for weeks. Eventually, the woman goes against her better judgement and begins to date him after he promises her a life of luxury and comfort.

Triggered by a fellow addict at a group therapy session, a man finds himself on the streets, in search of anything that will help him feel better.

A young teen in Southern California, after several months of living on the streets, tries to rebuild her life. She suddenly disappears after six months of sobriety, leaving her family to yet again wonder if she has relapsed and returned to live on the streets again.

A Native American man in Arizona is abandoned by his family on account of his alcoholism, leaving him to work with a local White ranch owner on the condition that he remain sober. Over the course of a year working there, he remains sober, and his wife considers moving back with their son, but his old friends and old habits return to tempt him towards addiction.

A recovered heroin addict begins to doubt that the man she ran away with knows what is best for her future.

A mother reflects on her past struggles with addiction.

A grieving sheriff takes it upon himself to battle the opium epidemic in his area after losing his nephew and wife to a drug dealer known only as the "hellbender."