A counselor breaks his sobriety streak after several meetings with a frustrating client. After arguing with his wife while drunk, the counselor begins to feel murderous and must fight his violent urges to earn back her trust.

When a sober woman in her thirties meets a strange man involved in high-profile drug deals, she is horrified to learn that he has followed her for weeks. Eventually, the woman goes against her better judgement and begins to date him after he promises her a life of luxury and comfort.

As he naviagtes his own sobriety, a man finds out that his best friend of twenty years has two months to live due to HIV/AIDS. With help from the dying friend's lover, the man helps prepare his friend for a final bronchoscopy.

A man, committed to sobering up, meets with two friends in a bar. Forced to accompany them in a late-night excursion for drugs, they find themselves in a strange and surreal night filled with broken glass, loose lizards, and group therapy.

A young teen in Southern California, after several months of living on the streets, tries to rebuild her life. She suddenly disappears after six months of sobriety, leaving her family to yet again wonder if she has relapsed and returned to live on the streets again.

A Native American man in Arizona is abandoned by his family on account of his alcoholism, leaving him to work with a local White ranch owner on the condition that he remain sober. Over the course of a year working there, he remains sober, and his wife considers moving back with their son, but his old friends and old habits return to tempt him towards addiction.

A mother reflects on her past struggles with addiction.

A woman addicted to narcotics works as a waitress and fixes up her apartment in hopes of getting back her son from foster care after throwing him against a wall.

An old drunk abuses his wife and children, which negatively impacts their lives in numerous ways. One day, the drunkard faces a tragic accident which allows his family to finally be free of his tyranny.

An alcoholic hospital janitor with a murky, dark family history meets a capricious woman with even worse substance abuse problems than him. As they get sober and build a relationship, a series of misfortunes at work drives him to confront his painful past and his understanding of death.