A young teen in Southern California, after several months of living on the streets, tries to rebuild her life. She suddenly disappears after six months of sobriety, leaving her family to yet again wonder if she has relapsed and returned to live on the streets again.

A woman addicted to narcotics works as a waitress and fixes up her apartment in hopes of getting back her son from foster care after throwing him against a wall.

When the father of her baby overdoses, a young mother with a crippling drug addiction hits rock bottom much faster than she thought possible. All the while, she must take care of her son and figure out how to survive.

In the 1990s, a 19-year-old aspiring actor-turned-construction worker develops an affinity for crack cocaine, making him doubt the promise of his future.

A grieving sheriff takes it upon himself to battle the opium epidemic in his area after losing his nephew and wife to a drug dealer known only as the "hellbender."

In downtown Houston, a teenage boy hustles for an older pimp and navigates an increasingly intimate relationship with one of his clients. He also keeps the pimp’s HIV diagnosis a secret from the rest of their crew.

As he flushes three decades of narcotics out of his system, an Arkansas man recalls a traumatic hunting trip into the woods with his father and his friends. In this memory, he finds the roots of both his addiction and his identity.

The stress of poverty drives a young man to commit a robbery. But when the deal goes south and someone is shot, he must hide from the law at his brother's place.

A car dealer’s deal with a drug dealer goes horribly wrong.

After Hurricane Katrina devastates New Orleans, an alcoholic leaves her apartment to loot—but when she's gravely injured by sharp debris, she has to rely on the kindness of others to reach safety in a dog-eat-dog world.