After a frustrating date—upset by the way even sex between women is shaped by patriarchal forces—a lesbian in NYC has sex with a male friend from college, determined to prioritize her pleasure over her learned instinct to satisfy the interests and egos of men.

In the near-future, hidden somewhere in the United States, lies the Institute, a center designed to help queer citizens lead normal, heterosexual lives via simulated reality experiments. However, when two young male employees start to meet in secret, they begin to question their jobs, their ever-fading memories, and the oddly familiar identities of their subjects. In the near future of the United States lies the Institute, where queer citizens learn how to lead happy, heterosexual lives with AI. One male employee, though, is struggling with his subject, and when he and a male coworker meet in secret to plan strategies for conversion, an unexpected spark begins his questioning of his fading memory, the rules of their workplace, and the odd familiarity of his subject.

A nurse finds that she cannot shake her discomfort with her daughter's sexuality after her daughter comes out as a lesbian. After she attends to a patient who is dying of AIDS, she comes to the realization that her homophobia contradicts her role as caregiver and mother.

To fulfill her mother’s dying wish, a woman tries to find the right man to have sex with just once.

A teenage girl mourns the loss of her beloved girlfriend to cancer as she begins a relationship with another girl who she realizes is no substitute.

A young, intersex outcast struggling to find their place in society finds solace in a beautiful visitor from another world. Despite having thoughts and motivations beyond human understanding, the two bond over their shared experiences and trauma, all the while battling ghosts from their past.

In Bulgaria, two men who met online play submissive and dominant roles in an innitially-consensual sexual encounter that turns into a violent assault.

In modern-day Los Angeles, a young lesbian woman lives next door to an actress she's been a fan of since the actress was an underground drag queen in New York. The actress pitches an idea for a TV show to the woman, whose partner is a children's show producer.

Nita, a young millennial in Chicago, decides to record interviews with her hook-ups as part of a sociologically-influenced art project. But when she falls in love with one of her subjects—a woman with an obscure past and a web of scars on her back—Nita finds herself drawn into a supernatural world from which she may never return.

When a lesbian Cuban woman moves to the United States, she finds her hopes of romantic relationships, familial reconciliation, and prosperity threatened by an onslaught of mysterious medical concerns.