When a man living in New York in the 1980s contracts HIV/AIDS, his friends constantly visit him in the hospital, leading to tears, drama, and questions of mortality and survival.

A woman posts an ad in a magazine for people positive for HIV and goes on dates with one degrading man after another, looking for someone to love.

In the far future, HIV cases skyrocket in South Africa, and chemists develop an expensive new drug that must be taken annually by those with the disease. When clinics start raising prices, a man attempts to steal the drug for his friend, only to be confronted with an ugly truth about the industry.

A nurse finds that she cannot shake her discomfort with her daughter's sexuality after her daughter comes out as a lesbian. After she attends to a patient who is dying of AIDS, she comes to the realization that her homophobia contradicts her role as caregiver and mother.

A plague targeting Black citizens sweeps the nation causing chaos and despair.

As he naviagtes his own sobriety, a man finds out that his best friend of twenty years has two months to live due to HIV/AIDS. With help from the dying friend's lover, the man helps prepare his friend for a final bronchoscopy.

In Bulgaria, two men who met online play submissive and dominant roles in an innitially-consensual sexual encounter that turns into a violent assault.

A research psychologist visits a peculiar asylum patient who recounts his life story. The patient warns the researcher about how obsession with the pursuit of knowledge can make one lose sight of their humanity until it is unsalvageable.

In the 1990s, as a mother watches her thirty-three-year old son slowly die from AIDS, she grows closer to him than she ever has before.

In 2018, a pedestrian on the New York City’s Lower East Side witnesses a young Black couple in love, prompting a consideration about the storytelling, hope, and Nelson Mandela.